Mitosis is a continuous process. The process is completed by a
complex method. According to the sequence
and stages, this continuous process is divided into five stages. The stages
are:
(1)Prophase,
(2) Pro-Metaphase,
(3) Metaphase,
(4) Anaphaseand
(5) Telophase.
Ø Prophase: At this stage, the nucleus swells up.Chromosomes
begin to be dehydrated. As a result, the chromosomes gradually become shorter
and thicker. Then they are visible under microscopes. At the end of this stage nucleolus
and nuclear membrane become disappear.
Ø Pro-Metaphase : At the beginning of this stage. the fibrous
protein converse toform a bi-polar spindle apparatus. Each chromosome is then
become attached to a fibre of the spindle apparatus by its centromere. Each
fibre of the spindle apparatus is called spindle fibre. The fibre to which the
chromosomes are attached is called traction fibre. As they are attached with
the chromosomes so they also called hromosomal fibre. In animal cell aster rays
re radiated from centrioles present at two poles.
Ø Metaphase: Chromosomes are arranged at the equatorial
plane of the spindle. The
centromere of each chromosome remains at the equatorial plane
and the two arms are placed towards two poles. At this stage, the chromosomes
become maximum thick and short. Two chromatids of a chromosome become maximum
thick and short. Two chromatids of a chromosome become clearly visible and the
centromere is divided in to two parts.
Ø Anaphase: Two separate chromatids of a chromosome move
towards the opposite pole of the spindle apparatus. Centromere goes ahead at
the movement of the chromatids towards the pole and the arms follow them. when
the daughter chromosomes reaches near the poles the anaphase stage ends.
Ø Telophase: Daughter chromosomes take position at two
opposite poles.Chromosomes gradually take water and become elongated, thin and
long. Nuclear membrane develops encircling the chromosomes. Nucleolus reappears
at the secondary constriction of the Sat chromosome. Spindle apparatus
disappears. At the end of this stage, gradually a cell wall develops at the
equatorial region of the cell. As a result, the mother cell divides into two
daughter cells. In case of animal cells, instead of formation of cell wall the
cell membrane is constricted inwardly and the cell divides into two.